2026년
한국질량분석학회 여름학술대회 및 총회
2026. 08.19 (수) ~ 2026. 08.21 (금)
창원컨벤션센터(CECO)
초록검색
| 제목 | Chemical Investigation of Kalopanax septemlobus Utilizing LC-MS/MS Associated with Molecular Network |
|---|---|
| 작성자 | 장서영 (순천대학교) |
| 발표구분 | 포스터발표 |
| 발표분야 | 2. Mass Spectrometry in Elemental Analysis |
| 발표자 |
Seoyeong Jang (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea) Eunyeong Jeong (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea, AI Bio Autonomous Research, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea, ) |
| 주저자 | Seoyeong Jang (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea) |
| 교신저자 |
Mina Lee (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea, College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, Suncheon, Jeonnam-Gwangj) |
| 저자 |
Seoyeong Jang (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea) Eunyeong Jeong (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea, AI Bio Autonomous Research, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea, ) Duc Dat Le (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea, College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, Suncheon, Jeonnam-Gwang) Thinhulinh Dang (College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea, Honam Regional Future Drug Development Convergence Education & Research Division (BK21 FOUR), ) Thientam Dinh (College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea, Honam Regional Future Drug Development Convergence Education & Research Division (BK21 FOUR), ) Soojung Yu (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea) Mina Lee (Department of Natural Cosmetics Science, Sunchon National University, Suncheon, Jeonnam-Gwangju 57922, Republic of Korea, College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, Suncheon, Jeonnam-Gwangj) |
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Kalopanax septemlobus (Thunb.) Koidz., a deciduous tree belonging to the Araliaceae family and widely distributed across East Asia, has traditionally been used to treat rheumatism, diabetes, and inflammatory disorders. In this study, we employed an untargeted metabolomic approach that combines liquid chromatography-tandem mass spectrometry (LC-MS/MS) with integrated molecular networking. This method allowed for a comprehensive annotation and visualization of the chemical constituents of young leaves and twigs of K. septemlobus, facilitating the rapid classification of structurally related groups of fatty acids, terpenoids, flavonoids, alkaloids, and phenylpropanoids based on MS/MS spectral similarity with both experimental and public mass databases. As a result, we annotated 32 chemical constituents with varying compositions present in the extracts of K. septemlobus. Among these, phenolics, terpenoids, and fatty acids were the primary groups of compounds, followed by organic acids, glycosides, flavonoids, and other groups. This integrated strategy offers a systematic framework for accelerating the discovery of bioactive metabolites that underpin the traditional therapeutic applications of K. septemlobus.
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